What are the signs of a Neurotransmitter Deficiency? Proper amounts of neurotransmitters are necessary for maintaining optimal mental and physical health. Common conditions associated with serotonin/dopamine deficiencies include: - PowerPoint PPT Presentation

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What are the signs of a Neurotransmitter Deficiency? Proper amounts of neurotransmitters are necessary for maintaining optimal mental and physical health. Common conditions associated with serotonin/dopamine deficiencies include:


What are the signs of a Neurotransmitter Deficiency? Proper amounts of neurotransmitters are necessary for maintaining optimal mental and physical health. – PowerPoint PPT presentation

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Title: What are the signs of a Neurotransmitter Deficiency? Proper amounts of neurotransmitters are necessary for maintaining optimal mental and physical health. Common conditions associated with serotonin/dopamine deficiencies include:

What are the signs of a Neurotransmitter
Deficiency?Proper amounts of neurotransmitters
are necessary for maintaining optimal mental and
physical health. Common conditions associated
with serotonin/dopamine deficiencies include
  • Appetite and Eating Disorders, especially binging
    or bulimia
  • Very strong cravings for sweets
  • Depression
  • Anxiety and Panic Attacks
  • Chronic fatigue
  • Fibromyalgia
  • Headaches-especially migraines
  • Premenstrual Syndrome
  • Seasonal Affective Disorder

  • Addictions
  • Attention Deficit Disorder
  • Chronic pain
  • Insomnia
  • Irritability and Anger Disorders
  • Low motivation
  • Compulsive Disorders
  • Decreased sex desire

  • Neurotransmitters are the chemicals that allow
    communication to occur in the brain.
  • DOPAMINE functions in
  • Feelings of pleasure/bliss
  • Feelings of attachment/love
  • Sense of altruism
  • Integration of thoughts and feelings (focused)
  • Appetite control
  • Controlled motor movements
  • Dopamine Deficiencies result in
  • Anhedonia (lack of pleasure)
  • Lack of ability to feel love and to love another
  • Lack of remorse about actions
  • Distractibility
  • Your world looks colorless

  • Norepinephrine functions in
  • Arousal, energy, drive, alertness
  • Stimulation
  • Fight or flight
  • Long-term memory and learning
  • Deficiencies result in
  • Lack of energy
  • Lack of motivation
  • First state called depression

  • Optimal levels can result in
  • Wellbeing or euphoric effect in stressful
  • Excess levels can result in
  • Fear and anxiety (as may be the case for those
    who suffer from anxiety disorders).

  • Norepinephrine is produced from dopamine with the
    help of amino acids phenylalanine, lysine, and
    methionine. Vitamin C and B-6, magnesium, and
    manganese are important cofactors.
  • Natural sources of building blocks
  • Almonds apples
  • Avocado bananas
  • Beef liver or kidney blue-green algae
  • Cheese fish
  • Most green vegetables
  • Lean meat nuts
  • Grains pineapple
  • Poultry tofu

  • Serotonin functions in
  • Emotional stability
  • Reduces aggression
  • Sensory input
  • Sleep cycle
  • Appetite control
  • Serotonin deficiencies result in
  • Irritability
  • Irrational emotions
  • Sudden unexplained tears
  • OCD
  • Sleep disturbances

  • Serotonin provides calming and stabilizing
  • Enough serotonin we feel emotionally stable, we
    can sleep, we can sort out feelings and determine
    in a logical manner if there is a threat present.
  • Low serotonin irritable, overly sensitive to
    sights and sounds. Difficulty sleeping and
    sudden outbursts of tears.
  • Enough serotonin
  • Hopeful/creative optimistic/focused
  • Calm/responsive patient/good natured
  • Loving/caring reflective/thoughtful
  • And---we dont CRAVE CARBOHYDRATES!

  • When we have a shortage of serotonin, lookout! We
  • Depressed Anxious Irritable Impatient
  • Impulsive Abusive Reactive A real Pain!
  • Plus we
  • Fly off the handle easily!!!!!!!!!
  • Have a short attention span
  • Seem to be blocked and scattered
  • Crave those sweets and high carbohydrates foods
  • Suffer from insomnia and have poor dream recall

  • Enkephalins/endorphins functions in
  • Internal calm
  • Sense of well-being
  • Feelings of euphoria
  • Self-concept
  • Pain management
  • Deficiencies result in
  • Internal turmoil
  • Lack of completeness
  • Sense of inadequacy
  • Poor pain control

  • What our body needs to supply Enkephalins
  • D-Phenylalanine Vitamin B6
  • Folic Acid
  • Natural sources of building blocks for
  • Fish Blue-green algae
  • Wheat germ green leafy vegetables
  • Tortula yeast egg yolks
  • (B-Complex)

  • GABA (gamma-aminobutyric acid)/it is really an
    amino acid but classified as a neurotransmitter.
  • Induces relaxation and sleep
  • Balances the brain where excitation is balanced
    with inhibition
  • Stimulates HGH(human growth hormone) HGH helps
    build muscle and prevent fat.
  • Slightly sedative effect best taken before
    going to bed.

  • What causes Neurotransmitter Deficiencies?
  • Here are some of the major reasons we can suffer
    from depressed neurotransmitter levels...
  • Prolonged Emotional or Physical Stress.
  • The human body is programmed to handle sudden,
    acute or short bouts of stress. Prolonged,
    chronic stress takes it toll on the fight or
    flight stress hormones and neurotransmitters.
    Eventually, these become depleted and coping
    becomes more difficult.

  • Aging.
  • 60 of all adults past age 40 have some degree of
    neurotransmitter deficiency. Aging neurons make
    smaller amounts of neurotransmitters. Also, as we
    get older, the body does not respond as well to
  • Weight Loss Dieting.
  • This is the most common cause of self-induced
    neurotransmitter deficiencies. Limiting food
    intake in order to lose weight restricts the
    amounts of basic building blocks
    (neurotransmitter precursors) needed to produce
    enough neurotransmitters

  • Studies from major universities, including
    Harvard, MIT, and Oxford, have documented that
    women on diets significantly deplete their
    serotonin within three weeks of dieting. This
    induced serotonin deficiency eventually leads to
    increased cravings, moodiness and poor
    motivation. These all contribute to rebound
    weight gain the most common yet unfortunate
    consequence of dieting.
  • Increasing neurotransmitter production during
    dieting is strongly encouraged to avoid yo-yo
    dieting. This is accomplished by taking dietary
    neurotransmitter precursor supplements during

  • Abnormal Sleep.
  • Many neurotransmitters responsible for proper
    sleep, especially serotonin, are produced during
    REM sleep around 2-3 a.m. Serotonin converts to
    melatonin, the sleep hormone. When serotonin
    levels are low, melatonin levels will also be
    low. Disrupted sleep occurs and less
    neurotransmitters are produced causing a vicious

  • Certain Medications.
  • Long-term use of diet pills, stimulants, pain
    pills, narcotics and recreational drugs can
    deplete neurotransmitter stores. The use of ma
    huang, ephedra and prescription diet pills (like
    phen-fen, Fastin, phentermine) use up large
    amounts of dopamine and serotonin. This can
    result in rebound appetite control problems,
    low energy, unstable mood and sluggish metabolism

  • Neurotoxins.
  • Heavy metal toxicity, chemical pesticides,
    fertilizers, certain cleaning agents, industrial
    solvents, and recreational drugs cause damage to
    the neuron and decrease neurotransmitter
    production. Excess caffeine, nicotine and alcohol
    can be neurotoxic. The street drug, Ecstasy, has
    particularly concerning neurotoxic effects. It
    can completely drain serotonin and permanently
    damage the neuron making treatment impossible

  • Hormone Imbalances.
  • Hormones influence neurotransmitter release and
    activity. If hormones are deficient or are off
    balance, neurotransmitters do not function well.
    Premenstrual Syndrome (PMS) is a classic example
    of how low serotonin levels can temporarily shift
    each month. Mood, appetite and sleep can be
    severely disrupted one to two weeks before the
    menstrual cycle.
  • Another neurotransmitter imbalance occurs during
    menopause when dramatic changes in mood, energy,
    sleep, weight, and sexual desire occur

  • Genetic Predisposition.
  • Some people are born with a limited ability to
    make adequate amounts of neurotransmitters. They
    exhibit deficiency symptoms as children or young
    adults and often have relatives who suffered from
    significant mental illnesses. As they get older,
    affected individuals experience even more
    profound symptoms and debilitation.

  • Traditional Medicine Treatments
  • As recently as the l970s the neuro-chemical
    pathways of the brain were not very well
    understood. There was very little in the way of
    successful treatments for mood disturbances.
    Electroconvulsive or shock therapy (ECT) was
    about the only effective treatment for resistant
    severe depression. We were unaware then of
    exactly how this therapy worked but now realize
    ECT works by artificially shocking
    neurotransmitters out of neurons. This flood of
    neurotransmitters results in marked improvement
    of depression.

  • The most commonly prescribed medications for
    abnormal moods (dysphoria) are the serotonin
    re-uptake inhibitors, called SRIs. These
    include Prozac, Paxil, Zoloft, Effexor, Serafem,
    Serzone, Celexa and Lexapro. SRIs prevent
    serotonin from reabsorbing back into storage
    vesicles. More serotonin then stays in the
    synapse, reattaching to receptors and stimulating
    more neurons

  • Alternative Medicine Treatments
  • Many alternative methods aimed at raising
    neurotransmitter levels have been widely used
    with reportedly good success, especially in Asia
    and Europe. These include acupuncture, hypnosis,
    massage, reflexology, meditation, yoga and herbal
    remedies. Neurotransmitter measurements of
    meditating Tibetan monks, showed increased levels
    of serotonin, the serenity messenger. With
    scientific data like this now supporting the
    benefits of these ancient treatments, more
    Western medical disciplines are becoming
    convinced and integrating them into their

  • The brain is a very hungry organ and a picky
  • You are what you eat!

  • Protein
  • Most neurotransmitters are made from protein or
    its subunits, amino acids. Eating adequate
    amounts of dietary protein is critical. The
    average person requires 40-70 grams (up to 90
    grams for a very active athlete) of protein

  • Serotonin originates from the amino acid
    tryptophan. Tryptophan is the least common amino
    acid in food. It is also the most difficult to
    absorb into the brain. These make serotonin
    synthesis more difficult. Although tryptophan is
    mainly found in fish, meat, dairy products, eggs,
    nuts and wheat germ, eating these does not
    substantially increase serotonin. This is because
    these foods contain other amino acids that
    compete with tryptophan for absorption.
    Tryptophan loses out to the other amino acids

  • Surprisingly, eating carbohydrates raises
    serotonin levels but eating protein decreases
    serotonin levels. Carbohydrates cause an insulin
    response that favors tryptophan absorption over
    other amino acids. This explains why many people
    who need more serotonin (like being
    overly-stressed or depressed) start to
    self-medicate by eating more sweets or starchy
    carbohydrates. As tryptophan absorption rises, so
    will serotonin production

  • Studies from Harvard, MIT and Oxford medical
    universities demonstrate that women on high
    protein/very low carbohydrate diets lower their
    serotonin levels, making them more prone to
    weight gain relapse, depression, excessive
    craving, bingeing, bulimia, severe PMS and
    seasonal affective disorder.

  • Dopamine is made from the amino acid tyrosine.
    Eating high protein foods promote dopamine
    production. Tyrosine is abundant and is found in
    chicken, fish, dairy products, almonds, avocados,
    bananas, legumes, soy products, pumpkin and
    sesame seeds

  • Carbohydrates
  • Dietary carbohydrates play a critical role in
    brain health. Women, especially, are vulnerable
    to how carbohydrates affect their moods.
    Serotonin, the main neurotransmitter for mood and
    appetite regulation, depends on carbohydrates for

  • Dr. Judith Wurtman from Massachusetts Institute
    of Technology (MIT) has published many articles
    linking serotonin deficiency conditions to low
    dietary carbohydrate intake. Women normally have
    one third less serotonin than men. Diets that
    severely restrict carbohydrates will result in
    even lower serotonin levels. Dr. Wurtman found
    that women on high protein/very low carbohydrate
    diets were at greater risk for depression,
    seasonal affective disorder (SAD), carbohydrate
    crave/binge disorder and severe premenstrual

  • Dietary Fat
  • About two thirds of our brain is made of fat
    (lipids). Lipids are incorporated into the brain
    cell walls promoting membrane flexibility and
    strength. A filmy fat layer covers the branches
    of neurons allowing proper electrical
    transmission of brain signals

  • Dietary Fat
  • Most lipids can be made directly by the body. But
    two lipids can come only from food. These fats
    are called essential fatty acids (EFA). The cell
    membranes of neurons are made from the essential
    fatty acids alpha-linoleic acid (ALA) and
    linoleic acid (LA).

  • Alpha-linoleic acid (ALA) belongs to the
    omega-3 fatty acid family. Main food sources of
    omega-3 ALA include flax seeds, walnuts, sea
    plants, green leafy vegetables, canola, soy, and
    walnut oil.
  • Linoleic acid (LA) belongs to the omega-6 fatty
    acid family. LA is found in the oils of seeds and
    nuts. Main food sources of omega 6 LA include
    expeller cold-pressed sunflower, safflower, corn
    and sesame oils

  • The most abundant fat in the brain is DHA
    (docosahexaenoic acid), an omega-3 fatty acid.
    Good dietary sources of DHA come from high-fat,
    cold water fish like salmon, sardines, mackerel
    and trout. DHA made from microalgae is also
    available in supplement capsules. DHA is
    identical to that found in neuron membranes.

  • Acetylcholine helpful in learning and memory.
    Made from B vitamins choline, found in eggs and
    organ meats, lecithin, and legumes/ 5 grams per
    day recommended dosage.
  • (Alzheimers is due in part to low acetylcholine
    as a result of death of the cholinergic neurons
    that make it).
  • B Vitamins aids in manufacturing
    neurotransmitters and regulating energy release
    in brain cells.
  • Thiamin (B1) Riboflavin (B2)
  • Niacin, pyridoxine (B6) Folic acid, biotin,
  • cobalimin

  • Supplements helpful to Brain Functioning
  • Multivitamins can raise non-verbal IQ scores
  • Antioxidants help clean up the brain like rust
    cleaners to help keep the rust off our brain
    matter.(prunes, raisins, blueberries,
    blackberries, garlic, cooked kale, cranberries,
    strawberries, raw spinach, raspberries).

  • Omega-3 helps brain functioning and mood.(tuna,
    salmon, mackerel, sardines, herring, oysters,
    walnuts, flax seed oil).
  • Selenium naturally elevates mood. (grains,
    garlic, meat, seafood and Brazil nuts).
  • Vitamin E blood circulation and heart
  • Folic Acid low levels result in depression and
    increases the risk for Alzheimers disease.

  • Ginko Biloba helps prevent memory loss.
    Increases circulation of oxygen and blood to the
  • Phosphatidylserine stimulates acetylcholine and
    improves memory.
  • Chromium suppresses a sharp rise in blood
  • B Vitamins helps combat stress. Improves
    memory and brain development.

  • If you listen to your body when it whispers, you
    wont have to listen to it when it screams at
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